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Since the Institute of Medicine first reviewed the health implications of national legalized abortion in 1975, there has been a plethora of related scientific research, including well-designed randomized clinical trials, systematic reviews, and epidemiological studies examining abortion care. This research has focused on examining the relative safety of abortion methods and the appropriateness of methods for different clinical circumstances. With this growing body of research, earlier abortion methods have been refined, discontinued, and new approaches have been developed. The Safety and Quality of Abortion Care in the United States offers a comprehensive review of the current state of the science related to the provision of safe, high-quality abortion services in the United States. This report considers 8 research questions and presents conclusions, including gaps in research. The development of safe and effective technique for 2nd trimester termination of pregnancy and intrauterine fetal death become a major clinical challenge. Different management protocols are continuously revised to achieve improved success rates and reduced discomfort for the patients. The introduction of PGs in the early 1970s has revolutionized the management protocols in this area. PG analogue alone or in combination with mifeprostone have been shown to be effective for the 2nd trimester termination of pregnancy. Misoprostol (Cytotec (R)) is a prostaglandin analogue which was developed for the prevention and treatment of gastroduodenal ulcers. Due to its properties of inducing ripening of the cervix and contractions of the pregnant uterus, it has also been found to be a very useful drug for several important indications in obstetrics. Although it is frequently used in many countries of the world, it is still not licensed for these indications and therefore in off-label use. Nevertheless, its use is still being discussed, as there are also repeated reports on serious adverse drug reactions, such as uterine rupture and maternal death, following the use of misoprostol in pregnant women. By pooling and evaluating data from studies investigating the use of misoprostol in its three main obstetrical indications (namely cervical ripening and labour induction, abortion induction, as well as the prevention and treatment of postpartum haemorrhage), published in the last twenty years, an overview of the available information on the efficacy and safety of misoprostol in obstetrics was provided. Medication abortion offers an alternative to Surgical Abortion for women in the early weeks of pregnancy. Medication abortion uses a combination of two medications, mifepristone and misoprostol, to end a pregnancy up to nine weeks. Medication abortion is a low-risk, non-invasive way to terminate (end) a pregnancy. It is around 99 per cent effective at ending a pregnancy. 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Medication abortion, also known as medical abortion or abortion with pills, is a pregnancy termination protocol that involves taking two different drugs, Mifepristone and misoprostol, that can be safely used up to the first 70 days (10 weeks) of pregnancy according to the U.S. Food and Drug Administration (FDA). The World Health Organization has authorized use to 12 weeks of pregnancy. Since the FDA first approved the drug in 2000, its use in the United States has quickly grown. By 2021, over half of abortions in the US were medication abortions. The medication abortion drug regimen approved by the FDA is available in many states across the nation, however, dispensing these pills for the purpose of terminating a pregnancy is now banned in some states. This factsheet provides an overview of medication abortion, how it is used and regulated, the role of the drug in self-managed abortions, and an analysis of the intersection of federal and state regulations pertaining to its provision and coverage. Abortion pill” is the common name for using two different medicines to end a pregnancy: mifepristone and misoprostol. First, you take a pill called mifepristone. Pregnancy needs a hormone called progesterone to grow normally. Mifepristone blocks your body’s own progesterone, stopping the pregnancy from growing. Then you take the second medicine, misoprostol, either right away or up to 48 hours later. This medicine causes cramping and bleeding to empty your uterus. It’s kind of like having a really heavy, crampy period, and the process is very similar to an early miscarriage. If you don’t have any bleeding within 24 hours after taking the second medicine, call your nurse or doctor. 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Suction is used to remove the fetus and related pregnancy material from the uterus. Before the procedure, you may have the following tests: A urine test checks if you are pregnant. A blood test checks your blood type. Based on the test result, you may need a special shot to prevent problems if you get pregnant in the future. The shot is called Rho(D) immune globulin . An ultrasound test checks how many weeks pregnant you are. Medical Abortion second methods use for pregnancy termination (abort) its called Medical abortion . This paper discusses choice and acceptability of medical abortion from the perspective of both women and abortion providers and argues that choice of method is important for both. Safety, efficacy, number of visits, how the method works, how long it takes for the abortion to be complete and cost all affect acceptability. 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Conclusion Abortion pills are a popular alternative for women seeking to terminate their pregnancy in Dubai. However, obtaining abortion pills without a prescription is illegal and can lead to serious consequences. It’s important to consider all options carefully and make an informed decision. If you’re considering obtaining abortion pills in Dubai, it’s important to consult with a medical professional and consider the legal and health risks. Abortion pills available in Dubai UAE In Dubai, abortion is only legal in cases where the mother's life is in danger, and even then, it must be approved by a panel of medical professionals. However, despite the strict laws surrounding abortion, some women may still seek out ways to terminate their pregnancies. If you are seeking abortion pills in Dubai, it is important to be aware of the risks involved in obtaining them. Purchasing abortion pills from unregulated sources can be dangerous and even life-threatening. Additionally, if you are found to be in possession of abortion pills in Dubai, you could face serious legal consequences. That being said, there are legal and safe options available for those who need them. Here are some places you can turn to for help: Dubai Health Authority (DHA) If you are seeking an abortion for medical reasons, the DHA may be able to provide assistance. They can help you determine whether or not you are eligible for a legal abortion, and if so, they can refer you to a medical facility where the procedure can be performed safely. Private Hospitals and Clinics in Dubai There are a number of private hospitals and clinics in Dubai that offer abortion services to patients who meet the legal requirements. These facilities are staffed by licensed medical professionals who can provide safe and legal abortions. It is important to do your research and choose a reputable medical facility that adheres to strict safety and sanitation protocols. This will ensure that you receive the best possible care during the procedure. Online Pharmacies in Dubai While it is not legal to purchase abortion pills in Dubai without a prescription, some online pharmacies may offer them for sale. However, it is important to exercise extreme caution when purchasing medications online. Many websites that claim to sell abortion pills are fraudulent and may not actually provide the products they advertise. If you do decide to purchase abortion pills online, be sure to research the website thoroughly and only purchase from a reputable source. You should also consult with a licensed medical professional before taking any medication. International Medical Facilities in Dubai If you are unable to obtain a legal abortion in Dubai, you may consider seeking treatment at an international medical facility. Some countries, such as India, offer safe and legal abortion services to foreign nationals. It is important to note, however, that traveling to another country for an abortion can be expensive and logistically challenging. Additionally, you should research the laws and regulations surrounding abortion in the country you plan to visit, as they may differ from those in Dubai. Conclusion Abortion is a sensitive topic, and seeking out abortion pills in Dubai can be risky. However, there are legal and safe options available for those who need them. Whether you choose to seek assistance from the DHA, a private medical facility, an online pharmacy, or an international medical facility, it is important to prioritize your safety and well-being. If you are unsure about how to proceed, consider speaking with a licensed medical professional who can provide guidance and support. They can help you navigate the legal and medical complexities of seeking an abortion in Dubai. Mifepristone & Misoprostol available in Dubai Mifepristone is a medication used for medical abortion. It is a synthetic steroid that works by blocking the hormone progesterone, which is needed for the maintenance of pregnancy. This causes the lining of the uterus to break down, and the pregnancy cannot continue to develop. On the other hand Misoprostol is used to induce labor, prevent stomach ulcers, and treat postpartum bleeding. It is also commonly used in combination with mifepristone for medical abortion. Mechanism of Mifepristone in UAE DUBAI: Mifepristone works by blocking the action of progesterone, a hormone that is essential for the maintenance of pregnancy. Progesterone is responsible for thickening the lining of the uterus, making it suitable for implantation of the fertilized egg. By blocking the action of progesterone, mifepristone causes the lining of the uterus to break down, and the pregnancy cannot continue to develop. It also softens and dilates the cervix, making it easier to expel the pregnancy. Dosage Use Unwanted pregnancy The standard dosage of mifepristone for medical abortion is 200 mg, taken orally with water. The medication is usually taken in a clinic or healthcare facility, under the supervision of a healthcare provider. The timing of the medication depends on the stage of pregnancy, but it is usually taken on the first day of the medical abortion process. After taking mifepristone, a second medication called misoprostol is usually taken within 24 to 48 hours. Misoprostol causes the uterus to contract and expel the pregnancy. The dosage and timing of misoprostol may vary depending on the specific medical abortion protocol used. Mifepristone And Misoprostol in DUBAI: Misoprostol works by causing the uterus to contract and expel its contents. When used for medical abortion, it is typically taken within 24 to 48 hours after mifepristone. The medication causes the uterus to contract, leading to the expulsion of the pregnancy. This process is similar to a natural miscarriage and usually involves heavy bleeding and cramping. In addition to its use in medical abortion, misoprostol is also used to induce labor. The medication is often given to women who are past their due date or who have medical conditions that require the baby to be delivered sooner. Misoprostol causes the cervix to soften and dilate, which can help induce labor. Misoprostol is also used to prevent stomach ulcers in people who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, or naproxen. NSAIDs can irritate the lining of the stomach and increase the risk of ulcers. Misoprostol helps protect the stomach by reducing the amount of acid produced and increasing the production of mucus, which helps protect the stomach lining. Another use of misoprostol is to treat postpartum bleeding. This medication is given to women after delivery to help prevent excessive bleeding. Misoprostol causes the uterus to contract, which can help stop bleeding and promote healing. It is important to note that misoprostol should only be used under the supervision of a healthcare provider, and in accordance with the appropriate medical protocol. Like any medication, misoprostol can cause side effects, such as nausea, vomiting, diarrhea, and abdominal pain. In rare cases, serious side effects such as allergic reactions or infection may occur, so it is important to seek medical attention if you experience any unusual symptoms. Dosage and Administration The standard dosage of Mifegest Kit is one Mifepristone tablet (200 mg) and four Misoprostol tablets (each 200 mcg). The tablets are taken in two different stages: On the first day, one Mifepristone tablet is taken orally, with or without food. On the third day, four Misoprostol tablets are taken buccally (placed in the cheek pouches) or vaginally (inserted into the vagina). It is important to follow the dosage instructions carefully, as taking too much or too little medication can affect the effectiveness of the abortion. Mifegest kit in Uae dubai Side Effects Like any medication, Mifegest Kit can cause side effects. Some of the common side effects include: Nausea and vomiting Diarrhea 00971 -508021841 Headache 00971 -508021841 Dizziness 00971 -508021841 Abdominal pain and cramping Heavy bleeding and clotting Most side effects are mild and go away on their own, but if they persist or worsen, it is important to contact a healthcare provider. In rare cases, serious side effects such as allergic reactions or infection may occur, so it is important to seek medical attention if you experience any unusual symptoms. FAQs Q: Is Mifegest Kit safe? A: Yes, Mifegest Kit is a safe and effective medication for terminating early pregnancy. 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